Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908355 | 0.83 | HDAC1 (0.52) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL4555559 | 0.72 | L3MBTL1 (0.70) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL9905717 | 0.71 | HDAC1 (0.52) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL29138798 | 0.71 | HDAC1 (0.55) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL30908462 | 0.71 | HDAC1 (0.54) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL29859557 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL287503 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL15966615 | 0.68 | TP53 (0.68) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL31087254 | 0.68 | TP53 (0.68) | ALDH1A1MAPTHTTL3MBTL1ALOX15 | |
| SCHEMBL2418750 | 0.68 | ALDH1A1 (0.62) | ALDH1A1MAPTHTTL3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |