Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555559 | 0.78 | L3MBTL1 (0.70) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL29138798 | 0.75 | HDAC1 (0.55) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL30908355 | 0.75 | HDAC1 (0.52) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL1612079 | 0.73 | MAOA (0.51) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1520536 | 0.72 | HDAC1 (0.70) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL27918500 | 0.71 | HDAC3 (0.65) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL28677805 | 0.71 | ALDH1A1 (0.78) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL30908319 | 0.71 | ALDH1A1 (0.52) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL6175231 | 0.71 | HDAC3 (0.73) | HDAC1HDAC3HDAC2HTTALDH1A1 | |
| SCHEMBL18086514 | 0.71 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |