Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 13/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908391 | 0.95 | TOP2A (0.35) | HDAC1TOP2ATOP2BGRM2SCN9A | |
| SCHEMBL30908422 | 0.86 | PLAU (0.42) | NOS1NOS2PLAU | |
| SCHEMBL30908503 | 0.84 | NPC1 (0.35) | HDAC1TOP2ATOP2BSCN9A | |
| SCHEMBL30908442 | 0.84 | AURKA (0.37) | HDAC1TOP2ATOP2BGRM2SCN9A | |
| SCHEMBL30908271 | 0.83 | PTPN1 (0.36) | TOP2ATOP2BSCN9A | |
| SCHEMBL30908572 | 0.82 | SCN9A (0.35) | NOS1NOS2PLAUSCN9A | |
| SCHEMBL30908483 | 0.82 | TSPO (0.39) | HDAC1TOP2ATOP2BSCN9A | |
| SCHEMBL30908418 | 0.81 | SCN9A (0.41) | TOP2ATOP2BSCN9A | |
| SCHEMBL30908423 | 0.81 | SCN9A (0.41) | TOP2ATOP2BSCN9A | |
| SCHEMBL30908596 | 0.79 | GSK3B (0.39) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |