Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14348206 | 0.85 | DHPS (0.54) | IDH1KDM4ECASP3MAPTAPP | |
| SCHEMBL31281346 | 0.81 | DCTPP1 (0.48) | DCTPP1GAACASP3MEN1APAF1 | |
| SCHEMBL31159232 | 0.81 | IDH1 (0.52) | IDH1KDM4EGAACASP3MEN1 | |
| SCHEMBL29506999 | 0.81 | IDH1 (0.52) | IDH1KDM4EGAACASP3MEN1 | |
| SCHEMBL30908544 | 0.81 | IDH1 (0.52) | IDH1KDM4EGAACASP3MAPT | |
| SCHEMBL25337041 | 0.81 | IDH1 (0.52) | IDH1KDM4EGAACASP3MEN1 | |
| SCHEMBL19582251 | 0.80 | DCTPP1 (0.45) | DCTPP1KDM4EGAACASP3MEN1 | |
| SCHEMBL1948769 | 0.79 | S100A4 (0.42) | IDH1GAAMAPTMEN1KMT2A | |
| SCHEMBL9933768 | 0.78 | IDH1 (0.45) | IDH1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL3381771 | 0.78 | DHPS (0.41) | CASP3MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720060-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024240894-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-11-28 | — | — | WO | disclosed |
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |