Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908531 | 0.81 | TLR7 (0.39) | KMT2ATLR7GRM5CYP11B2KDM4E | |
| SCHEMBL26606901 | 0.80 | KMT2A (0.39) | KMT2ACA1CA2GRM5CYP11B2 | |
| SCHEMBL2419272 | 0.78 | POLB (0.44) | KMT2APOLBALDH1A1 | |
| SCHEMBL30908438 | 0.78 | KDM4E (0.45) | KMT2ACA1CA2CYP11B2LMNA | |
| SCHEMBL8141883 | 0.77 | ACHE (0.40) | KDM4E | |
| SCHEMBL832390 | 0.73 | MAOA (0.47) | KMT2APOLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL857068 | 0.71 | HSD17B14 (0.41) | CA1CA2CYP11B2KDM4EALDH1A1 | |
| SCHEMBL30353359 | 0.71 | VCAM1 (0.44) | CA1CA2SLC6A4 | |
| SCHEMBL533946 | 0.71 | ALDH1A1 (0.42) | NPC1LMNATP53POLBMAPT | |
| SCHEMBL406876 | 0.71 | VCAM1 (0.44) | CA1CA2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |