Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12875937 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRTP53THRBHSD17B10 | |
| Hydrochloric Acid SCHEMBL1198489 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRTP53THRB | |
| SCHEMBL13437369 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1NPSR1THRBHPGD | |
| SCHEMBL7838351 | 0.81 | SMN1; SMN2 (0.31) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL21765808 | 0.80 | CES2 (0.41) | SMN1; SMN2TSHRCES2CES1HDAC8 | |
| Hydrochloric Acid SCHEMBL22683491 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1NPSR1SLC6A3THRB | |
| SCHEMBL10901570 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRCES2CES1HDAC8 | |
| SCHEMBL3826078 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRCES2CES1HDAC8 | |
| SCHEMBL24520292 | 0.75 | CES2 (0.44) | TSHRCES2CES1HDAC8HDAC6 | |
| SCHEMBL1617657 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRCES2CES1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650185-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BETA-HYDROXY- ALPHA-AMINOCARBOXYLIC ACID DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2013-05-01 | — | — | EP | disclosed |
| EP-1650185-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BETA-HYDROXY- ALPHA-AMINOCARBOXYLIC ACID DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2013-05-01 | — | — | EP | disclosed |
| US-7799941-B2 | Process for producing optically active β-hydroxy-α-aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799941-B2 | Process for producing optically active β-hydroxy-α-aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20060167300-A1 | Process for producing optically active ss-hydroxy alpha aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1650185-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BETA-HYDROXY- ALPHA-AMINOCARBOXYLIC ACID DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167300-A1 | Process for producing optically active ss-hydroxy alpha aminocarboxylic acid derivative | ALDH7A1, HCAR1, ALAD | SMN1; SMN2 3508/4885TSHR 2932/4885CES2 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.