Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 9/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | IDE | P14735 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.50 |
| ▸ | S100A10 | P60903 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15708668 | 1.00 | USP2 (0.61) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL15731850 | 0.88 | ALDH1A1 (0.64) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL15708667 | 0.81 | NPSR1 (0.50) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL4210842 | 0.76 | MAPT (1.00) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL26763552 | 0.64 | ALDH1A1 (0.62) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL26762398 | 0.64 | ALDH1A1 (0.73) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL4206962 | 0.61 | HCRTR2 (0.76) | USP2ALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL13563348 | 0.60 | HTT (0.55) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4205329 | 0.60 | PTGES (0.59) | USP2NPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL4202757 | 0.59 | PTGES (1.00) | USP2NPSR1ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11975032-B2 | Medicament for liver regeneration and for treatment of liver failure | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11975032-B2 | Medicament for liver regeneration and for treatment of liver failure | PYGL, HNF4A, ATF1 | USP2 3155/4885NPSR1 4538/4885ALDH1A1 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.