Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.62 |
| ▸ | USP2 | O75604 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 11/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 12/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | IDE | P14735 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26762398 | 0.92 | ALDH1A1 (0.73) | ALDH1A1NPSR1USP2KDM4ECREBBP | |
| SCHEMBL26764564 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPSR1USP2KDM4ECREBBP | |
| SCHEMBL26762394 | 0.69 | ALDH1A1 (0.48) | ALDH1A1NPSR1USP2KDM4ECREBBP | |
| SCHEMBL18036488 | 0.65 | TPH2 (0.87) | ALDH1A1USP2MAPK1 | |
| SCHEMBL15731850 | 0.64 | ALDH1A1 (0.64) | ALDH1A1NPSR1USP2KDM4ETSHR | |
| SCHEMBL30919384 | 0.64 | USP2 (0.61) | ALDH1A1NPSR1USP2KDM4ECREBBP | |
| SCHEMBL15708668 | 0.64 | USP2 (0.61) | ALDH1A1NPSR1USP2KDM4ECREBBP | |
| SCHEMBL9665330 | 0.61 | RAB9A (0.52) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL6247201 | 0.61 | TSHR (0.73) | ALDH1A1NPSR1KDM4ETSHRPOLB | |
| SCHEMBL9667095 | 0.59 | NPC1 (0.71) | ALDH1A1KDM4EPOLBHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | The University of Pittsburgh- of the Commonwealth System of Higher Education | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357261-A1 | ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS | AHR, ARNT, MTNR1A | ALDH1A1 752/4885NPSR1 390/4885USP2 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.