Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 14/20 | 0.58 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.58 |
| ▸ | BMP2K | Q9NSY1 | 3/20 | 0.58 |
| ▸ | GAK | O14976 | 2/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.58 |
| ▸ | MYLK2 | Q9H1R3 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.50 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.50 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.50 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24897751 | 1.00 | AAK1 (0.58) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL27220588 | 0.88 | TGFBR1 (0.49) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL30185619 | 0.84 | AAK1 (0.62) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL24897652 | 0.84 | AAK1 (0.62) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL21508497 | 0.78 | AAK1 (0.56) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL25983881 | 0.78 | AAK1 (0.55) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL25595134 | 0.77 | AAK1 (0.47) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL30185675 | 0.76 | AAK1 (0.77) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL24897635 | 0.76 | AAK1 (0.77) | AAK1DAPK1MKNK2BMP2KGAK | |
| SCHEMBL30185612 | 0.76 | AAK1 (0.77) | AAK1DAPK1MKNK2BMP2KGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343720-A1 | AAK1 INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-10-17 | — | — | US | disclosed |
| EP-4371980-A1 | AAK1 INHIBITOR AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343720-A1 | AAK1 INHIBITOR AND USE THEREOF | AAK1, ADCK1, ADCK5 | AAK1 1/4885DAPK1 52/4885MKNK2 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.