Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | EDNRA | P25101 | 4/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CKS1B | P61024 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30925503 | 0.86 | SLC40A1 (0.39) | HTR6SLC40A1ADRA1AGLO1ALDH1A1 | |
| SCHEMBL30925408 | 0.78 | ALDH1A1 (0.40) | HTR6SLC40A1KDM4ETSHRADRA1A | |
| SCHEMBL26964541 | 0.77 | EDNRA (0.34) | HTR6EDNRASLC40A1KDM4ENSD2 | |
| SCHEMBL29800372 | 0.77 | EDNRA (0.34) | HTR6EDNRASLC40A1KDM4ENSD2 | |
| SCHEMBL30553443 | 0.74 | HTR6 (0.33) | HTR6ADRA1AALDH1A1 | |
| SCHEMBL26964497 | 0.74 | HTR6 (0.33) | HTR6ADRA1AALDH1A1 | |
| SCHEMBL30925478 | 0.72 | CARM1 (0.34) | HTR6ADRA1AALDH1A1 | |
| SCHEMBL30925521 | 0.72 | GLO1 (0.59) | SLC40A1GLO1ALDH1A1AGTR1TDP1 | |
| SCHEMBL27214186 | 0.72 | GLO1 (0.59) | SLC40A1GLO1ALDH1A1AGTR1TDP1 | |
| SCHEMBL29800922 | 0.72 | EDNRA (0.37) | HTR6EDNRASLC40A1KDM4ENSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ZOETIS LLC | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ARSA, MRPS2, SULT2A1 | HTR6 3742/4885EDNRA 1570/4885SLC40A1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.