Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981241 | 0.73 | RAB9A (0.41) | NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL6037395 | 0.72 | KMT2A (0.47) | NPC1RAB9AMAPTGAAKMT2A | |
| SCHEMBL8429803 | 0.72 | AKR1C3 (0.46) | PGRADORA3PTGS1SLC6A2NPC1 | |
| SCHEMBL11063218 | 0.72 | PTGS2 (0.40) | PGRADORA3PTGS1SLC6A2KMT2A | |
| SCHEMBL6432858 | 0.71 | KMT2A (0.46) | NPC1RAB9AMAPTGAAKMT2A | |
| SCHEMBL6171373 | 0.71 | ALDH1A1 (0.42) | HPGDGAAKMT2AALDH1A1TSHR | |
| SCHEMBL3082586 | 0.71 | NPC1 (0.49) | NPC1RAB9AHPGDGAAKMT2A | |
| SCHEMBL5161099 | 0.70 | KDM4E (0.44) | NPC1RAB9AMAPTGAAKMT2A | |
| SCHEMBL28891951 | 0.70 | NPC1 (0.41) | NPC1RAB9AHPGDGAAKMT2A | |
| SCHEMBL6690434 | 0.70 | PTGS2 (0.43) | PGRADORA3PTGS1SLC6A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |