Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 10/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604134 | 1.00 | L3MBTL1 (0.47) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL13157806 | 1.00 | L3MBTL1 (0.47) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL3100379 | 0.95 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL13604130 | 0.95 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL13157797 | 0.95 | TP53BP1 (0.54) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL3107837 | 0.90 | TP53BP1 (0.39) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL13157813 | 0.90 | TP53BP1 (0.39) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL13157799 | 0.86 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL13604133 | 0.86 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 | |
| SCHEMBL3098557 | 0.86 | L3MBTL1 (0.45) | L3MBTL1TP53BP1L3MBTL3MAPK10MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CXCR2 | L3MBTL1 4317/4885TP53BP1 3833/4885L3MBTL3 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.