Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904252 | 0.91 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL3080647 | 0.91 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL4603071 | 0.91 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL1040785 | 0.86 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL4501713 | 0.86 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL4615166 | 0.85 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL4616826 | 0.84 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL4616996 | 0.83 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL24238334 | 0.83 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL663968 | 0.83 | CNR1 (0.66) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799804-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2010-09-21 | — | — | US | disclosed |
| US-7799804-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2010-09-21 | — | — | US | disclosed |
| US-7799804-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2010-09-21 | — | — | US | disclosed |
| US-20090005415-A1 | 1,2-Diarylimidazoles for Use as Cb1 Modulators | ASTRAZENECA AB (SE) | 2009-01-01 | — | — | US | disclosed |
| US-20080319019-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319019-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319019-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | disclosed |
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | disclosed |
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | disclosed |
| EP-1940803-A1 | 1,2-DIARYLIMIDAZOLES FOR USE AS CBI MODULATORS | AstraZeneca AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1940820-A1 | MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS | AstraZeneca AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1833802-A2 | 1,2-DIPHENYL-IMIDAZOLE DERIVATIVES AND THEIR USE AS CB1 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| US-20070208059-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2007-09-06 | — | — | US | disclosed |
| US-20070208059-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2007-09-06 | — | — | US | disclosed |
| US-20070208059-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2007-09-06 | — | — | US | disclosed |
| WO-2007031720-A1 | 1,2-DIARYLIMIDAZOLES FOR USE AS CBI MODULATORS | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007031721-A1 | MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007031721-A1 | MIDAZOLE-4-CARBOXAMIDE DERIVATIVES FOR USE AS CB MODULATORS | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006067428-A2 | 1, 2-DIPHENYL-IMIDAZOLE DERIVATIVES AND THEIR USE AS CB1 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306115-A1 | Midazole-4-Carboxamide Derivatives For Use As Cb1 Modulators | CNR2, CNR1, FAAH | CNR1 2/4885CNR2 1/4885 |
| US-20090005415-A1 | 1,2-Diarylimidazoles for Use as Cb1 Modulators | CNR2, CNR1, FAAH | CNR1 2/4885CNR2 1/4885 |
| US-20070208059-A1 | Therapeutic Agents | NLN, BDNF, GAP43 | CNR1 193/4885CNR2 254/4885 |
| US-20080319019-A1 | Therapeutic Agents | SDHA, GPR119, ABAT | CNR1 393/4885CNR2 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.