Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279491 | 0.86 | ALDH1A1 (0.67) | HCAR3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL6142287 | 0.85 | ALDH1A1 (0.52) | HCAR3LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL5552716 | 0.85 | ALDH1A1 (0.58) | HCAR3ALDH1A1MAPTPOLBTSHR | |
| SCHEMBL109334 | 0.81 | ALDH1A1 (0.77) | HCAR3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL1885551 | 0.78 | HCAR3 (0.48) | HCAR3LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL5839671 | 0.77 | ALDH1A1 (0.61) | HCAR3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL2716434 | 0.77 | LMNA (0.70) | HCAR3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL18075204 | 0.76 | HCAR3 (0.67) | HCAR3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL15595336 | 0.76 | LMNA (0.68) | HCAR3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL15774731 | 0.76 | LMNA (0.68) | HCAR3LMNAALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | claimed |
| US-7799093-B2 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | L'ORéAL S.A. (FR) | 2010-09-21 | — | — | US | disclosed |
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | L'OREAL S.A. (FR) | 2008-06-05 | — | — | US | disclosed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | HCAR3 2420/4885LMNA 800/4885ALDH1A1 18/4885 |
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | KRT18, PUF60, VIM | HCAR3 3619/4885LMNA 649/4885ALDH1A1 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.