Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109266 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HCAR3LMNA | |
| SCHEMBL29829407 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HCAR3LMNA | |
| SCHEMBL5839671 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1HCAR3LMNA | |
| SCHEMBL30808004 | 0.85 | ALDH1A1 (0.85) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL198602 | 0.85 | ALDH1A1 (0.85) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| SCHEMBL8799830 | 0.84 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1HCAR3LMNA | |
| SCHEMBL111343 | 0.84 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL9820092 | 0.84 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1HCAR3MAPT | |
| Hydrochloric Acid SCHEMBL8974864 | 0.83 | ALDH1A1 (0.86) | ALDH1A1TSHRTDP1HCAR3LMNA | |
| SCHEMBL210589 | 0.83 | ALDH1A1 (0.85) | ALDH1A1TSHRTDP1HCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | claimed |
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | claimed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | claimed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | claimed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | claimed |
| US-5972044-A | Composition and method for dyeing keratin fibers | WELLA AG (DE) | 1999-10-26 | — | — | US | claimed |
| EP-0867170-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | claimed |
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | claimed |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-12-31 | — | — | US | disclosed |
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-08 | — | — | US | disclosed |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-01 | — | — | US | disclosed |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-09-24 | — | — | US | disclosed |
| EP-0806199-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1997-11-12 | — | — | EP | disclosed |
| EP-0796850-A1 | 4,5-Diiminopyrazolines, their process of preparation and dyeing compositions containing them | L'OREAL (FR) | 1997-09-24 | — | — | EP | disclosed |
| EP-0659399-B1 | Process of direct hair using steam | OREAL (FR) | 1997-03-19 | — | — | EP | disclosed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | disclosed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | ALDH1A1 18/4885TSHR 4753/4885TDP1 758/4885 |
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 40/4885TSHR 4836/4885TDP1 1560/4885 |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | ALDH1A1 87/4885TSHR 2949/4885TDP1 3522/4885 |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 26/4885TSHR 4819/4885TDP1 1390/4885 |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 28/4885TSHR 4771/4885TDP1 1004/4885 |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 37/4885TSHR 4846/4885TDP1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.