Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034534 | 0.69 | KDM4E (0.66) | TNKS2PARP2KDM4EALDH1A1APOBEC3G | |
| SCHEMBL30939171 | 0.66 | AKT1 (0.36) | KDM4EAKT1AKT2 | |
| SCHEMBL7224848 | 0.64 | GABRG2 (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2AKT1 | |
| SCHEMBL31728622 | 0.63 | ADORA3 (0.42) | KDM4EALDH1A1SMN1; SMN2AKT1AKT2 | |
| SCHEMBL14685157 | 0.62 | GPR139 (0.37) | AKT1AKT2 | |
| SCHEMBL31729104 | 0.61 | GPR139 (0.39) | KDM4EALDH1A1MPIGAAAKT1 | |
| SCHEMBL7225919 | 0.61 | KDM4E (0.40) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL15767066 | 0.57 | SUV39H2 (0.32) | KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8710795 | 0.56 | BRD9 (0.40) | MAPTSMN1; SMN2TDP1LMNANCOA1 | |
| SCHEMBL160602 | 0.55 | BTK (0.47) | KDM4EALDH1A1HPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215477-A | Mitochondrial pyruvate carrier inhibitors [1,2,4] triazolo [4,3-a ] pyrimidin-7 (8H) -one for the treatment of cancer | MPC治疗中心 | 2024-06-18 | — | — | CN | disclosed |