Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981184 | 0.82 | PNMT (0.41) | PNMTFOLH1NPC1RAB9AITGB3 | |
| SCHEMBL28512979 | 0.81 | ACE (0.38) | PNMTFOLH1 | |
| Triphenylmethanol SCHEMBL15361971 | 0.81 | PNMT (0.36) | PNMTNPC1RAB9AITGB3ITGA2B | |
| SCHEMBL30148112 | 0.81 | ACE (0.38) | PNMTFOLH1 | |
| SCHEMBL30027910 | 0.81 | ACE (0.38) | PNMTFOLH1 | |
| SCHEMBL29168371 | 0.80 | CTSK (0.40) | PNMTNPC1RAB9AITGB3ITGA2B | |
| SCHEMBL6022774 | 0.80 | ITGB3 (0.44) | PNMTFOLH1NPC1RAB9AITGB3 | |
| SCHEMBL6022733 | 0.80 | ITGB3 (0.44) | PNMTFOLH1NPC1RAB9AITGB3 | |
| SCHEMBL27658685 | 0.80 | PNMT (0.38) | PNMTNPC1RAB9AITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL28300337 | 0.79 | PNMT (0.38) | PNMTFOLH1NPC1RAB9AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153243-A1 | MODIFIED PEPTIDE AS TREM-1 INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118359676-A | Modified peptides as Trem-1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-07-19 | — | — | CN | disclosed |