Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275826 | 0.98 | CES1 (0.54) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| SCHEMBL8921169 | 0.83 | CYP3A4 (0.66) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| SCHEMBL30940459 | 0.82 | CYP3A4 (0.63) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| SCHEMBL11878518 | 0.80 | CYP3A4 (0.52) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| SCHEMBL8517083 | 0.80 | CYP3A4 (0.52) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| SCHEMBL11878522 | 0.80 | CYP3A4 (0.52) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| SCHEMBL11876245 | 0.78 | CYP3A4 (0.50) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| Phenylacetic Acid SCHEMBL541980 | 0.78 | CES1 (0.71) | CES1CES2CYP3A4CYP2C9AKR1B1 | |
| Phenylpyruvate SCHEMBL9218269 | 0.76 | CES1 (0.76) | CES1CES2AKR1B1FNTAFNTB | |
| SCHEMBL9456021 | 0.76 | CYP3A4 (0.47) | CES1CES2CYP3A4CYP2C9AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118367119-A | Organic matter modified carbon-based negative electrode material and manufacturing method thereof | 贵州创德新能源科技有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118367119-A | Organic matter modified carbon-based negative electrode material and manufacturing method thereof | 贵州创德新能源科技有限公司 | 2024-07-19 | — | — | CN | disclosed |