Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30856788 | 1.00 | MEN1 (0.45) | MEN1KMT2AENPP2PTGS2L3MBTL1 | |
| SCHEMBL29488687 | 0.78 | PSIP1 (0.56) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL22518691 | 0.78 | PSIP1 (0.56) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL9625997 | 0.77 | TSHR (0.52) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL11664636 | 0.77 | CA2 (0.52) | MEN1KMT2A | |
| SCHEMBL15550610 | 0.76 | ENPP2 (0.52) | ENPP2PTGS2 | |
| SCHEMBL18770137 | 0.72 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL25803446 | 0.72 | ENPP2 (0.35) | MEN1KMT2AENPP2PTGS2 | |
| SCHEMBL1272514 | 0.71 | GPR84 (0.45) | MEN1KMT2A | |
| SCHEMBL27571145 | 0.71 | KEAP1 (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |