Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP4 | P49662 | 1/20 | 0.53 |
| ▸ | CASP5 | P51878 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20876007 | 0.86 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1TSHRHDAC1HDAC4 | |
| SCHEMBL3276896 | 0.85 | CASP1 (0.64) | ALDH1A1TSHRHSD17B10HDAC1HDAC4 | |
| SCHEMBL1160126 | 0.85 | SIGMAR1 (0.62) | SIGMAR1HDAC1HDAC4KCNH2CXCR4 | |
| Bicarbonate SCHEMBL21981463 | 0.85 | SIGMAR1 (0.85) | SIGMAR1ALDH1A1TSHRHDAC1HDAC4 | |
| SCHEMBL28206349 | 0.84 | CASP1 (0.62) | ALDH1A1TSHRHSD17B10HDAC1HDAC4 | |
| SCHEMBL13995932 | 0.84 | SIGMAR1 (0.61) | SIGMAR1HDAC1HDAC4KCNH2CXCR4 | |
| Hydrochloric Acid SCHEMBL28273325 | 0.84 | SIGMAR1 (0.61) | SIGMAR1HDAC1HDAC4KCNH2CXCR4 | |
| Hydrochloric Acid SCHEMBL10901935 | 0.84 | SIGMAR1 (0.61) | SIGMAR1HDAC1HDAC4KCNH2CXCR4 | |
| SCHEMBL3282966 | 0.84 | CASP1 (0.62) | ALDH1A1TSHRHSD17B10HDAC1HDAC4 | |
| Acetic Acid SCHEMBL7452259 | 0.82 | SIGMAR1 (0.79) | SIGMAR1ALDH1A1TSHRCXCR4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303544-A1 | LMO2 PROTEIN INHIBITORS | UNIV OF OXFORD (GB) | 2023-09-28 | — | — | US | disclosed |
| US-20230303544-A1 | LMO2 PROTEIN INHIBITORS | UNIV OF OXFORD (GB) | 2023-09-28 | — | — | US | disclosed |
| CN-110167626-B | Low friction seal | 苏尔莫迪克斯公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-108348728-B | Hemodialysis catheter sleeve | 苏尔莫迪克斯公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-107666872-B | Insertable medical device system with plaque treatment portion and method of use thereof | 舒尔默迪克斯公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-106794283-B | Article coating comprising oligomeric polyphenol layer and methods of biological use thereof | 舒尔默迪克斯公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-104185661-B | The lubricity medical treatment device coating of low microgranule | 苏尔莫迪克斯公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2838577-A1 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY | SurModics, Inc. (US) | 2015-02-25 | — | — | EP | disclosed |
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2359943-B1 | ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF | SURMODICS INC (US) | 2014-01-22 | — | — | EP | disclosed |
| US-20100189877-A1 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES | SURMODICS, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100096320-A1 | Ultra-thin photo-polymer coatings and uses thereof | SURMODICS, INC. | 2010-04-22 | — | — | US | disclosed |
| EP-1893703-B1 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES | SURMODICS INC (US) | 2009-12-30 | — | — | EP | disclosed |
| EP-1945380-A2 | ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF | SurModics, Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1893703-A2 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES | SurModics, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1858438-A2 | COMPLIANT POLYMERIC COATINGS FOR INSERTABLE MEDICAL ARTICLES | SurModics, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2007056338-A2 | ULTRA-THIN PHOTO-POLYMERIC COATINGS AND USES THEREOF | SURMODICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2006130776-A2 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES | SURMODICS, INC. (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006099470-A2 | COMPLIANT POLYMERIC COATINGS FOR INSERTABLE MEDICAL ARTICLES | SURMODICS, INC. (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20060210816-A1 | Compliant polymeric coatings for insertable medical articles | BANK OF MONTREAL, AS COLLATERAL AGENT | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303544-A1 | LMO2 PROTEIN INHIBITORS | LMNB2, LMNB1, TPX2 | SIGMAR1 1454/4885ALDH1A1 3524/4885USP2 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.