Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL30944833 | 0.94 | UGT2B7 (0.36) | UGT2B7GRIN1GRIN2BCDC25ALMNA | |
| Adipic Acid SCHEMBL6552402 | 0.63 | LMNA (0.58) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL9436956 | 0.62 | LMNA (0.50) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL27756876 | 0.62 | LMNA (0.73) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL15633992 | 0.62 | LMNA (0.44) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL27831179 | 0.61 | LMNA (0.55) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL28454650 | 0.61 | LMNA (0.55) | LMNAAKR1B1HSD17B10 | |
| Adipic Acid SCHEMBL9294379 | 0.60 | LMNA (0.69) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL5311340 | 0.60 | LMNA (0.79) | LMNAAKR1B1MEN1KMT2AHSD17B10 | |
| Adipic Acid SCHEMBL4353087 | 0.60 | LMNA (0.79) | LMNAAKR1B1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12013523-B2 | Immersion oils having long service life | CARL ZEISS JENA GMBH (DE) | 2024-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12013523-B2 | Immersion oils having long service life | DGKI, CCNE2, CYCS | UGT2B7 3447/4885GRIN1 4606/4885GRIN2B 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.