Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.64 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.64 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017191 | 0.80 | GNAI3 (0.97) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL6135546 | 0.79 | GNAI3 (0.69) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| Hydrochloric Acid SCHEMBL20542952 | 0.78 | GNAI3 (1.00) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL4555068 | 0.78 | GNAI3 (0.94) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL1104022 | 0.77 | NAAA (0.43) | GNAI3GNAO1GNAI1NAAAKMT2A | |
| SCHEMBL19309524 | 0.76 | GNAI3 (0.64) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL1438748 | 0.76 | GNAI3 (0.84) | GNAI3GNAO1GNAI1NAAAKMT2A | |
| SCHEMBL670169 | 0.73 | GNAI3 (0.60) | GNAI3GNAO1GNAI1NAAAKMT2A | |
| SCHEMBL19064233 | 0.72 | GNAI3 (0.81) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL20142152 | 0.72 | GNAI3 (0.63) | GNAI3GNAO1GNAI1NAAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146234-A | 6,5,7,6-Tetracyclic derivatives, preparation method and application thereof | 浙江我武翼方药业有限公司 | 2024-06-07 | — | — | CN | disclosed |