Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 9/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22246276 | 0.90 | EGFR (0.49) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL22246232 | 0.88 | MAPK9 (0.55) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL30503703 | 0.88 | MAPK9 (0.55) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL22246265 | 0.85 | EGFR (0.53) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL30948585 | 0.85 | CCNK (0.52) | MAPK9MAPK10EGFRMAPK8ALK | |
| Trifluoroacetic Acid SCHEMBL29065781 | 0.84 | MAPK9 (0.55) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL30503700 | 0.83 | EGFR (0.48) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL22246247 | 0.81 | EGFR (0.52) | MAPK9MAPK10EGFRMAPK8ALK | |
| SCHEMBL22520178 | 0.81 | ALK (0.44) | EGFRALK | |
| SCHEMBL30948620 | 0.81 | EGFR (0.49) | MAPK9MAPK10EGFRALKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |