Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174932 | 0.80 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL5031603 | 0.79 | NR3C2 (0.44) | NR3C2DHODHHDAC6 | |
| SCHEMBL5466767 | 0.77 | LMNA (0.51) | DHODHHDAC6TRPV1NOTUM | |
| SCHEMBL358590 | 0.77 | ALDH1A1 (0.47) | DHODHHDAC6TRPV1L3MBTL1 | |
| SCHEMBL29564876 | 0.77 | ALDH1A1 (0.47) | DHODHHDAC6TRPV1L3MBTL1 | |
| SCHEMBL29128723 | 0.76 | IDH2 (0.44) | DHODHHDAC6TRPV1NOTUMIDH2 | |
| SCHEMBL514543 | 0.75 | HTT (0.50) | DHODHHDAC6L3MBTL1 | |
| SCHEMBL17506268 | 0.75 | NPC1 (0.51) | HDAC6NOTUML3MBTL1 | |
| SCHEMBL30986038 | 0.75 | MEN1 (0.63) | TRPV1 | |
| SCHEMBL4566108 | 0.75 | MAPT (0.61) | DHODHHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245702-A1 | Inhibition of Lysine Demethylase 1 (Lsd1) Induces Differentiation of Hair Cells | MASSACHUSETTS EYE AND EAR INFIRMARY | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245702-A1 | Inhibition of Lysine Demethylase 1 (Lsd1) Induces Differentiation of Hair Cells | KDM7A, KDM1B, KDM1A | NR3C2 2606/4885DHODH 219/4885HDAC6 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.