Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948733 | 0.85 | SMN1; SMN2 (0.33) | L3MBTL1KMT2APOLBFAAH | |
| SCHEMBL30948663 | 0.84 | ALDH1A1 (0.32) | L3MBTL1FAAHALDH1A1KDM4E | |
| SCHEMBL18451341 | 0.84 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBFAAHNOD1 | |
| SCHEMBL20465422 | 0.84 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBFAAHNOD1 | |
| SCHEMBL30948678 | 0.83 | CTSK (0.31) | L3MBTL1FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29530690 | 0.83 | TLR2 (0.32) | L3MBTL1KMT2AFAAHALDH1A1HPGD | |
| SCHEMBL26940602 | 0.83 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBFAAHNOD1 | |
| SCHEMBL30682184 | 0.83 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBFAAHNOD1 | |
| SCHEMBL15362363 | 0.83 | CYP1A2 (0.52) | L3MBTL1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL17933289 | 0.83 | CYP1A2 (0.52) | L3MBTL1KMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246902-A1 | PRODRUGS OF 6-DIAZO-5-OXO-L-NORLEUCINE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246902-A1 | PRODRUGS OF 6-DIAZO-5-OXO-L-NORLEUCINE | GLUL, GLS, GLS2 | L3MBTL1 320/4885KMT2A 1705/4885POLB 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.