SCHEMBL30949321

SCHEMBL30949321

O=C(Nc1ccc(Oc2ccc3c(c2)C(=O)NC3=O)cc1)Nc1cccc(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
HPGD P15428 3/20 0.59
TSHR P16473 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
RXFP1 Q9HBX9 1/20 0.58
CDK8 P49336 3/20 0.57
GSK3B P49841 1/20 0.56
POLB P06746 1/20 0.56
MAPT P10636 4/20 0.54
HTT P42858 3/20 0.54
USP2 O75604 1/20 0.54
ALOX15 P16050 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
LMNA P02545 2/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30949328 0.86 RXFP1 (0.76) MEN1KMT2AHPGDTSHRSMN1; SMN2
SCHEMBL5639582 0.77 CASP3 (0.66) MEN1KMT2AHPGDTSHRSMN1; SMN2
SCHEMBL30949348 0.76 GSK3B (0.67) MEN1KMT2AHPGDTSHRSMN1; SMN2
SCHEMBL7574156 0.76 MEN1 (0.57) MEN1KMT2AHPGDTSHRSMN1; SMN2
SCHEMBL15141492 0.75 MEN1 (0.77) MEN1KMT2ATSHRSMN1; SMN2CDK8
SCHEMBL22103801 0.74 TP53 (0.75) MEN1KMT2ATSHRSMN1; SMN2L3MBTL1
SCHEMBL30949332 0.74 GSK3B (0.67) MEN1KMT2AHPGDTSHRSMN1; SMN2
SCHEMBL14514335 0.74 PKM (0.64) MEN1KMT2AHPGDRXFP1POLB
SCHEMBL30949320 0.74 KMT2A (0.76) MEN1KMT2AHPGDTSHRSMN1; SMN2
SCHEMBL30949324 0.74 KMT2A (0.58) MEN1KMT2AHPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP claimed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO claimed
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP disclosed
WO-2024153736-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2024-07-25 WO disclosed