Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949539 | 0.74 | CNR2 (0.36) | CNR2CNR1FAAHHTR3EHTR3B | |
| SCHEMBL30949552 | 0.72 | DHPS (0.39) | MEN1KMT2ANPC1RAB9AHTR3E | |
| SCHEMBL30949607 | 0.72 | POLB (0.43) | CNR2MEN1KMT2ACNR1FAAH | |
| SCHEMBL30949600 | 0.72 | AHR (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL13987128 | 0.70 | NR4A2 (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL3456991 | 0.66 | CNR2 (0.56) | CNR2MEN1KMT2AFAAHPOLB | |
| SCHEMBL30949498 | 0.66 | EPHX2 (0.38) | CNR2MEN1KMT2ACNR1FAAH | |
| SCHEMBL3459501 | 0.64 | CNR2 (0.57) | CNR2MEN1KMT2AFAAHPOLB | |
| SCHEMBL30949599 | 0.61 | P2RX7 (0.36) | — | |
| SCHEMBL28305040 | 0.61 | CNR2 (1.00) | CNR2CNR1FAAHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |