Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987128 | 0.77 | NR4A2 (0.47) | AHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30949600 | 0.76 | AHR (0.46) | AHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23701819 | 0.73 | DHPS (0.63) | DHPSIMPDH2MEN1NPC1KMT2A | |
| SCHEMBL30949503 | 0.72 | CNR2 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30949614 | 0.72 | EGLN1 (0.34) | DHPSJAK2ANO1 | |
| SCHEMBL30949609 | 0.72 | ALPL (0.34) | DHPSJAK2HTR3EHTR3BHTR3A | |
| SCHEMBL8995172 | 0.68 | AHR (0.52) | AHRP2RX7PARP1 | |
| SCHEMBL30949604 | 0.68 | RAB9A (0.36) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30949502 | 0.68 | POLB (0.41) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7753609 | 0.67 | MAOA (0.53) | IMPDH2NPC1RAB9AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |