Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625928 | 1.00 | ULK1 (0.35) | ULK1MAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL23625920 | 0.89 | KDM4E (0.39) | MAPTKMT2AL3MBTL1MEN1PGR | |
| SCHEMBL30952915 | 0.89 | KDM4E (0.39) | MAPTKMT2AL3MBTL1MEN1PGR | |
| SCHEMBL24852671 | 0.87 | MEN1 (0.42) | MAPTKMT2AL3MBTL1MEN1POLB | |
| SCHEMBL24823372 | 0.86 | ALDH1A1 (0.34) | MAPTL3MBTL1PGRNPC1RAB9A | |
| SCHEMBL30039556 | 0.85 | MAPT (0.41) | MAPTKMT2AL3MBTL1POLB | |
| SCHEMBL23626139 | 0.85 | MAPT (0.41) | MAPTKMT2AL3MBTL1POLB | |
| SCHEMBL30952889 | 0.76 | RAB9A (0.37) | MAPTKMT2AL3MBTL1MEN1POLB | |
| SCHEMBL23625903 | 0.76 | RAB9A (0.37) | MAPTKMT2AL3MBTL1MEN1POLB | |
| SCHEMBL24852676 | 0.76 | ALDH1A1 (0.46) | MAPTKMT2AL3MBTL1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767090-B | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-28 | — | — | CN | disclosed |