Furan

Furan

SCHEMBL3095660

O=C1C=Cc2ccc3ccccc3c2C1=O.c1ccoc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.81
ALDH1A1 P00352 6/20 0.41
LMNA P02545 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 2/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
DNMT1 P26358 1/20 0.40
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
HSD17B10 Q99714 2/20 0.37
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380656 0.90 CES1 (1.00) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL29460197 0.82 CES1 (0.83) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL22609991 0.81 CES1 (0.81) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL5716919 0.79 CES1 (0.79) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL7213583 0.76 CES1 (0.72) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL87570 0.74 CES1 (0.70) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL7577681 0.73 CES1 (0.61) CES1ALDH1A1LMNAMEN1KMT2A
SCHEMBL23043820 0.71 ALDH1A1 (0.69) CES1ALDH1A1LMNAMEN1KMT2A
Phenanthrene SCHEMBL27796933 0.71 ALDH1A1 (0.67) ALDH1A1LMNAHPGDMAPK1CYP1A2
1,2-Naphthoquinone SCHEMBL28785542 0.69 PTPRC (0.77) CES1ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234453-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM KT & G CO., LTD. (KR) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234453-A1 PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM SLC10A2, SI, ABCB11 CES1 1053/4885ALDH1A1 2943/4885LMNA 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.