SCHEMBL380656

SCHEMBL380656

O=C1C=Cc2ccc3ccccc3c2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 1.00
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 2/20 0.47
MAPK1 P28482 2/20 0.47
USP2 O75604 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX12 P18054 1/20 0.47
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
DNMT1 P26358 1/20 0.47
MAPT P10636 3/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
BCHE P06276 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460197 0.91 CES1 (0.83) CES1ALDH1A1MEN1KMT2ALMNA
Furan SCHEMBL3095660 0.90 CES1 (0.81) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL22609991 0.90 CES1 (0.81) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL5716919 0.88 CES1 (0.79) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL7213583 0.84 CES1 (0.72) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL87570 0.82 CES1 (0.70) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL23043820 0.79 ALDH1A1 (0.69) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL7577681 0.77 CES1 (0.61) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL4449670 0.74 CES1 (0.59) CES1ALDH1A1MEN1KMT2ALMNA
SCHEMBL1055359 0.72 CES1 (0.56) CES1ALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552956-B2 Photopolymerizable type dental surface coating composition SHOFU INC. (JP) 2026-02-17 US claimed
CN-1300145-C Indoline spirophenanthroline compound and synthesis method and application thereof PHYSICS & CHEMISTRY INST CHINE (CN) 2007-02-14 CN claimed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
US-12552956-B2 Photopolymerizable type dental surface coating composition SHOFU INC. (JP) 2026-02-17 US disclosed
US-RE50759-E1 Dental composite material having stable pasty property SHOFU INC. (JP) 2026-01-27 US disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
EP-4656175-A1 DENTAL CEMENT AND DENTAL CEMENT PREPARATION KIT Tokuyama Dental Corporation (JP) 2025-12-03 EP disclosed
EP-4652959-A1 DENTAL SYRINGE Shofu Inc. (JP) 2025-11-26 EP disclosed
US-20250195339-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2025-06-19 US disclosed
EP-0490862-A1 Process for producing n-phosphonomethylglycine MONSANTO COMPANY (US) 1992-06-17 EP disclosed
US-5072033-A N-phosphonomethyl iminodiacetic acid oxidized with peroxide in the presence of cobalt or vandadium salt and quinone or deriv ative MONSANTO COMPANY (US) 1991-12-10 US disclosed
EP-0399985-A2 Process for producing N-phosphonomethylglycine MONSANTO COMPANY (US) 1990-11-28 EP disclosed
US-4937376-A Using oxidation catalyst mixture of metal salt, and (hydro)quinone MONSANTO COMPANY (US) 1990-06-26 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 CES1 4623/4885ALDH1A1 3441/4885MEN1 3431/4885
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 CES1 451/4885ALDH1A1 314/4885MEN1 2022/4885
US-12552956-B2 Photopolymerizable type dental surface coating composition CDH1, DCLRE1A, ITGA1 CES1 3078/4885ALDH1A1 50/4885MEN1 2636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.