Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93609 | 0.97 | FDPS (0.46) | FDPSDNM1TSHRLMNASMPD1 | |
| Bromide SCHEMBL4472153 | 0.94 | FDPS (0.41) | FDPSDNM1TSHRLMNASMPD1 | |
| Bromide SCHEMBL3842068 | 0.94 | FDPS (0.44) | FDPSDNM1TSHRSMPD1THRB | |
| Iodide SCHEMBL553007 | 0.93 | FDPS (0.44) | FDPSDNM1TSHRLMNASMPD1 | |
| Water SCHEMBL661747 | 0.93 | FDPS (0.44) | FDPSDNM1TSHRLMNASMPD1 | |
| Fluoride SCHEMBL4871826 | 0.93 | FDPS (0.44) | FDPSDNM1TSHRLMNASMPD1 | |
| Hydrochloric Acid SCHEMBL363004 | 0.93 | FDPS (0.44) | FDPSDNM1TSHRLMNASMPD1 | |
| SCHEMBL3643521 | 0.90 | FDPS (0.42) | FDPSDNM1TSHRLMNASMPD1 | |
| SCHEMBL346990 | 0.90 | FDPS (0.46) | FDPSDNM1TSHRSMPD1THRB | |
| SCHEMBL516377 | 0.90 | FDPS (0.42) | FDPSDNM1TSHRLMNASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | ENTEGRIS INC (US) | 2026-01-15 | — | — | US | claimed |
| CN-113441178-B | TiO 2 Application of SAPO-5 catalyst in preparation of cycloalkyl-substituted aromatic hydrocarbon by using low-carbon alkylating agent and method thereof | 西北大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115368477-A | Preparation method of carboxyl maltose iron with high yield and high iron content | 武汉科福新药有限责任公司 | 2022-11-22 | — | — | CN | claimed |
| US-11434201-B2 | Processes for preparing pyrrolidine compounds | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-09-06 | — | — | US | claimed |
| CN-112552517-B | Hyperbranched polymer viscosity reducer for high-strength concrete and preparation method thereof | 中建西部建设建材科学研究院有限公司 | 2022-04-01 | — | — | CN | claimed |
| EP-3661915-B1 | PROCESSES FOR PREPARING PYRROLIDINE COMPOUNDS | VERTEX PHARMA (US) | 2022-03-09 | — | — | EP | claimed |
| CN-113441178-A | TiO2Application of/SAPO-5 catalyst in preparation of cycloalkyl substituted aromatic hydrocarbon by low-carbon alkylating agent and method | 西北大学 | 2021-09-28 | — | — | CN | claimed |
| CN-113372549-A | Vinyl-terminated hyperbranched polymer, viscosity-reducing polycarboxylate superplasticizer with hyperbranched structure and preparation method of viscosity-reducing polycarboxylate superplasticizer | 中建西部建设建材科学研究院有限公司 | 2021-09-10 | — | — | CN | claimed |
| US-20210246117-A1 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2021-08-12 | — | — | US | claimed |
| CN-112552517-A | Hyperbranched polymer viscosity reducer for high-strength concrete and preparation method thereof | 中建西部建设建材科学研究院有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-111051280-A | Process for producing pyrrolidine compound | 弗特克斯药品有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-108219128-B | Preparation method of cement dispersant with sulfate adaptability and viscosity reduction effect | 江苏苏博特新材料股份有限公司 | 2019-12-27 | — | — | CN | claimed |
| WO-2019113476-A2 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-06-13 | — | — | WO | claimed |
| WO-2019028228-A1 | PROCESSES FOR PREPARING PYRROLIDINE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-02-07 | — | — | WO | claimed |
| US-9522915-B2 | Method for preparing an important intermediate of linagliptin | 2Y-CHEM, LTD. (CN) | 2016-12-20 | — | — | US | claimed |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | 2Y-CHEM, LTD. (CN) | 2015-10-01 | — | — | US | claimed |
| US-20090253746-A1 | Synthesis and Preparations of Intermediates and New Polymorphs Thereof Useful For The Preparation Of Donepezil Hydrochlcoride | MEDICHEM S.A. (ES) | 2009-10-08 | — | — | US | claimed |
| EP-1960357-A2 | SYNTHESIS AND PREPARATIONS OF INTERMEDIATES AND POLYMORPHS THEREOF USEFUL FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE | Medichem S.A. (ES) | 2008-08-27 | — | — | EP | claimed |
| WO-2007119118-A2 | SYNTHESIS AND PREPARATIONS OF INTERMEDIATES AND POLYMORPHS THEREOF USEFUL FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE | MEDICHEM S.A. (US) | 2007-10-25 | — | — | WO | claimed |
| US-4487722-A | Method of preparing 4-(α-hydrocarbyl-α-cyanomethyl)2,6-di-substituted phenols | ETHYL CORPORATION (US) | 1984-12-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246117-A1 | PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SCNN1G | FDPS 185/4885DNM1 943/4885TSHR 2590/4885 |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | DPP4, DPP9, DPP3 | FDPS 1255/4885DNM1 4278/4885TSHR 3222/4885 |
| US-11434201-B2 | Processes for preparing pyrrolidine compounds | MTAP, PRMT5, TET3 | FDPS 650/4885DNM1 201/4885TSHR 1970/4885 |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | TET2, ASIC1, PIEZO1 | FDPS 4294/4885DNM1 2538/4885TSHR 2647/4885 |
| US-20090253746-A1 | Synthesis and Preparations of Intermediates and New Polymorphs Thereof Useful For The Preparation Of Donepezil Hydrochlcoride | CYP2E1, DRD4, COMT | FDPS 3192/4885DNM1 107/4885TSHR 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.