Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 3/20 | 0.44 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93609 | 0.97 | FDPS (0.46) | FDPSTSHRLMNASMPD1THRB | |
| Water SCHEMBL3484908 | 0.94 | FDPS (0.44) | FDPSTSHRSMPD1THRBTNNC1 | |
| Water SCHEMBL3485636 | 0.94 | FDPS (0.41) | FDPSTSHRLMNASMPD1THRB | |
| Hydrochloric Acid SCHEMBL363004 | 0.93 | FDPS (0.44) | FDPSTSHRLMNASMPD1THRB | |
| Bromide SCHEMBL309594 | 0.93 | FDPS (0.44) | FDPSTSHRLMNASMPD1THRB | |
| Iodide SCHEMBL553007 | 0.93 | FDPS (0.44) | FDPSTSHRLMNASMPD1THRB | |
| Fluoride SCHEMBL4871826 | 0.93 | FDPS (0.44) | FDPSTSHRLMNASMPD1THRB | |
| SCHEMBL3643521 | 0.90 | FDPS (0.42) | FDPSTSHRLMNASMPD1THRB | |
| SCHEMBL346990 | 0.90 | FDPS (0.46) | FDPSTSHRSMPD1THRBTNNC1 | |
| Water SCHEMBL3486009 | 0.90 | FDPS (0.46) | FDPSTSHRSMPD1THRBTNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260150612-A1 | SURFACE CONDITIONING PROCESSES FOR SEMICONDUCTOR PROCESSING CHAMBER PARTS | APPLIED MATERIALS, INC (US) | 2026-05-28 | — | — | US | claimed |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | ENTEGRIS INC (US) | 2026-01-15 | — | — | US | claimed |
| EP-3894512-B1 | COMPOSITION AND METHOD FOR SELECTIVELY ETCHING RUTHENIUM AND/OR COPPER | ENTEGRIS INC (US) | 2025-12-24 | — | — | EP | claimed |
| US-20250333849-A1 | SOLVENT-BASED COMPOSITIONS AND RELATED METHODS FOR MOLYBDENUM ETCHING | ENTEGRIS INC (US) | 2025-10-30 | — | — | US | claimed |
| US-12331012-B2 | Organic catalyst for non-aqueous aldol condensation | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-06-17 | — | — | US | claimed |
| CN-119923173-B | N-type doping method of organic semiconductor and application thereof | 宁波天璇新材料科技有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119923173-A | N-type doping method of organic semiconductor and application thereof | 宁波天璇新材料科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-115461318-B | Organic catalyst for non-aqueous aldol condensation | 陶氏环球技术有限责任公司 | 2025-04-29 | — | — | CN | claimed |
| CN-118994585-A | High-refractive-index fluorosilicone liquid and preparation method thereof | 深圳市冠恒新材料科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| EP-4429802-A1 | MEMBRANE FOR REMOVING ANIONIC MATERIALS | Entegris, Inc. (US) | 2024-09-18 | — | — | EP | claimed |
| US-6103100-A | CORROSION RESISTANCE IN CRUDE OIL DISTILLATION | BETZDEARBORN INC. (US) | 2000-08-15 | — | — | US | claimed |
| WO-2000001785-A1 | METHODS AND COMPOSITIONS FOR INHIBITING CORROSION | BETZDEARBORN INC. (US) | 2000-01-13 | — | — | WO | claimed |
| EP-0642483-B1 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF | DOW CHEMICAL CO (US) | 1998-02-18 | — | — | EP | claimed |
| EP-0642483-A4 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF. | — | 1995-04-19 | — | — | EP | claimed |
| EP-0642483-A1 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1995-03-15 | — | — | EP | claimed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | claimed |
| EP-0611366-A1 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-08-24 | — | — | EP | claimed |
| US-5227560-A | Vinylene or exomethylene groups from active methine compounds | THE DOW CHEMICAL COMPANY (US) | 1993-07-13 | — | — | US | claimed |
| WO-1993009078-A1 | CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | claimed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260150612-A1 | SURFACE CONDITIONING PROCESSES FOR SEMICONDUCTOR PROCESSING CHAMBER PARTS | ASH2L, KCNH3, H1-2 | FDPS 4882/4885THRB 3974/4885MEN1 2024/4885 |
| US-12331012-B2 | Organic catalyst for non-aqueous aldol condensation | C9, ENO1, C1S | FDPS 2742/4885THRB 4882/4885MEN1 1777/4885 |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | TET2, ASIC1, PIEZO1 | FDPS 4294/4885THRB 2810/4885MEN1 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.