Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 10/20 | 0.47 |
| ▸ | JUN | P05412 | 6/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.47 |
| ▸ | RELA | Q04206 | 6/20 | 0.47 |
| ▸ | ATF1 | P18846 | 5/20 | 0.42 |
| ▸ | XPO1 | O14980 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962609 | 0.80 | NFKB1 (0.43) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30962658 | 0.78 | NFKB1 (0.42) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30962633 | 0.74 | NFKB1 (0.42) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30962791 | 0.73 | NFKB1 (0.50) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL22145341 | 0.69 | KMT2A (0.45) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30962738 | 0.69 | PDE4D (0.39) | NFKB1ATF1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL24951632 | 0.69 | RAB9A (0.52) | NFKB1JUNNFKB2RELAHSD17B10 | |
| SCHEMBL22145717 | 0.69 | MAPT (0.54) | NFKB1JUNNFKB2RELAALDH1A1 | |
| SCHEMBL20558428 | 0.68 | NFKB1 (0.65) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30962773 | 0.67 | PDE4D (0.38) | NFKB1JUNNFKB2RELAATF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |