Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.50 |
| ▸ | JUN | P05412 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATF1 | P18846 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088827 | 0.74 | HTT (0.61) | KMT2APPARGSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16088601 | 0.73 | KMT2A (0.51) | KMT2APPARGMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30962629 | 0.73 | NFKB1 (0.44) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30962852 | 0.73 | NFKB1 (0.47) | NFKB1JUNNFKB2RELAKMT2A | |
| SCHEMBL19347293 | 0.73 | EGLN1 (0.69) | KMT2AMEN1ALDH1A1PKM | |
| SCHEMBL23864300 | 0.72 | KMT2A (0.47) | KMT2APPARGMEN1SMN1; SMN2HPGD | |
| SCHEMBL13170059 | 0.71 | ALDH1A1 (0.54) | KMT2AMEN1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22145717 | 0.71 | MAPT (0.54) | NFKB1JUNNFKB2RELAKMT2A | |
| SCHEMBL24951632 | 0.71 | RAB9A (0.52) | NFKB1JUNNFKB2RELAKMT2A | |
| SCHEMBL2946609 | 0.71 | NFKB1 (0.52) | NFKB1JUNNFKB2RELAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642767-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | Acrivon Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |