Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | VDR | P11473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964248 | 0.79 | DRD2 (0.68) | DRD2DRD3ADRA1APOLBDRD4 | |
| SCHEMBL4686773 | 0.76 | MAPT (0.62) | MAPTTSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL1374049 | 0.75 | KMT2A (0.60) | MAPTTSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL7058045 | 0.73 | DRD2 (0.75) | DRD2DRD3ADRA1AHSD17B10 | |
| SCHEMBL4685459 | 0.73 | DRD2 (0.63) | MAPTLMNADRD2DRD3TP53 | |
| SCHEMBL30964242 | 0.73 | DRD2 (0.62) | SMN1; SMN2DRD2DRD3ADRA1ADRD4 | |
| SCHEMBL5863404 | 0.73 | LMNA (0.74) | MAPTTSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL5577816 | 0.72 | ALDH1A1 (0.62) | MAPTLMNASMN1; SMN2DRD2DRD3 | |
| SCHEMBL4689185 | 0.72 | DRD2 (0.62) | MAPTLMNADRD2DRD3TP53 | |
| SCHEMBL4684210 | 0.72 | DRD2 (0.59) | DRD2DRD3ADRA1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |