Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.68 |
| ▸ | DRD4 | P21917 | 12/20 | 0.68 |
| ▸ | DRD3 | P35462 | 12/20 | 0.68 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964242 | 0.94 | DRD2 (0.62) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL14495145 | 0.80 | DRD2 (0.75) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL29799578 | 0.79 | DRD2 (0.73) | DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL30964237 | 0.79 | MAPT (0.59) | DRD2DRD4DRD3ADRA1APOLB | |
| SCHEMBL7052714 | 0.78 | DRD2 (0.70) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL14495136 | 0.76 | DRD2 (0.73) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL14494896 | 0.76 | DRD2 (0.63) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL30964278 | 0.76 | CXCR3 (0.55) | DRD2DRD3HTR1AHTR2AMEN1 | |
| SCHEMBL14494899 | 0.74 | DRD2 (0.59) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL30964241 | 0.74 | HTR1A (0.51) | DRD2DRD3HTR1AHTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |