Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.62 |
| ▸ | DRD4 | P21917 | 8/20 | 0.62 |
| ▸ | DRD3 | P35462 | 5/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964248 | 0.94 | DRD2 (0.68) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL14495145 | 0.78 | DRD2 (0.75) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL30964278 | 0.77 | CXCR3 (0.55) | DRD2DRD3HTR1AHTR2AMAPK1 | |
| SCHEMBL14494896 | 0.77 | DRD2 (0.63) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL14494899 | 0.76 | DRD2 (0.59) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL30964241 | 0.75 | HTR1A (0.51) | DRD2DRD3HTR1AHTR2AMAPK1 | |
| SCHEMBL14494916 | 0.75 | DRD2 (0.63) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL14495136 | 0.74 | DRD2 (0.73) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL30964256 | 0.74 | HTR1A (0.56) | DRD2DRD3HTR1AHTR2AMAPK1 | |
| SCHEMBL7052714 | 0.73 | DRD2 (0.70) | DRD2DRD4DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |