Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965247 | 0.96 | S1PR5 (0.38) | NAAACYSLTR2CYSLTR1GAAHTT | |
| SCHEMBL30965245 | 0.92 | MCL1 (0.38) | NAAAMCL1BCL2A1NMT1FABP4 | |
| SCHEMBL30965221 | 0.85 | MCL1 (0.40) | MCL1BCL2A1ACLYPTGDR2 | |
| SCHEMBL30965263 | 0.81 | MCL1 (0.39) | CYSLTR2CYSLTR1GAAMCL1BCL2A1 | |
| SCHEMBL30965222 | 0.81 | CYP19A1 (0.39) | NAAACYSLTR2CYSLTR1S1PR5ASAH1 | |
| SCHEMBL30965253 | 0.77 | WDR5 (0.43) | TSHRHTTS1PR5ACLYHPGD | |
| SCHEMBL30965160 | 0.76 | S1PR5 (0.41) | NAAACYSLTR2CYSLTR1GAAS1PR5 | |
| SCHEMBL30965207 | 0.76 | MCL1 (0.41) | MCL1BCL2A1KMT2APTGDR2 | |
| SCHEMBL30965270 | 0.75 | HPGD (0.41) | NAAACYSLTR2CYSLTR1GAAHTT | |
| SCHEMBL30965259 | 0.73 | S1PR5 (0.42) | NAAACYSLTR2CYSLTR1GAAS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125964-A | Isoindoline-1, 3-diketone mPGES-1 inhibitor and application thereof | 长江大学 | 2024-06-04 | — | — | CN | disclosed |