Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965199 | 0.96 | NAAA (0.36) | S1PR5HPGDNAAAACLYMEN1 | |
| SCHEMBL30965245 | 0.91 | MCL1 (0.38) | MAPK1NAAAMEN1KMT2AMCL1 | |
| SCHEMBL30965263 | 0.85 | MCL1 (0.39) | S1PR5MAPK1ACLYMEN1KMT2A | |
| SCHEMBL30965221 | 0.81 | MCL1 (0.40) | ALDH1A1ACLYMCL1BCL2A1 | |
| SCHEMBL30965160 | 0.81 | S1PR5 (0.41) | S1PR5HPGDNAAAALDH1A1MEN1 | |
| SCHEMBL30965264 | 0.77 | ACLY (0.44) | S1PR5MAPK1ALDH1A1ACLYMEN1 | |
| SCHEMBL30965222 | 0.76 | CYP19A1 (0.39) | S1PR5NAAAALDH1A1CYSLTR2CYSLTR1 | |
| SCHEMBL30965207 | 0.75 | MCL1 (0.41) | ALDH1A1KMT2AMCL1BCL2A1 | |
| SCHEMBL30965220 | 0.75 | S1PR5 (0.42) | S1PR5HPGDNAAAALDH1A1MEN1 | |
| SCHEMBL30965262 | 0.74 | MEN1 (0.46) | S1PR5HPGDMAPK1NAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125964-A | Isoindoline-1, 3-diketone mPGES-1 inhibitor and application thereof | 长江大学 | 2024-06-04 | — | — | CN | disclosed |