SCHEMBL30965317

SCHEMBL30965317

N=C1C(C(=O)O)=C(c2ccccc2)C(=N)C(C(=O)O)=C1c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.52
FGFR2 P21802 4/20 0.52
FGFR4 P22455 4/20 0.52
FGFR3 P22607 4/20 0.52
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 1/20 0.43
XBP1 P17861 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HKDC1 Q2TB90 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SRC P12931 2/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
CDC25B P30305 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656807 0.74 FGFR1 (0.70) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL29273155 0.74 FGFR1 (0.70) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL30965323 0.74 ALDH1A1 (0.42) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL30965319 0.74 ALDH1A1 (0.45) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL9651512 0.70 FGFR1 (0.53) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL13770821 0.68 FGFR1 (0.85) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL147279 0.68 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL188149 0.68 PTGS2 (0.53) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL5138388 0.67 FGFR1 (0.65) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL15881020 0.65 TP53 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325078-A Preparation method and application of benzoquinone conjugated polymer 中国科学院宁波材料技术与工程研究所 2024-07-12 CN claimed
CN-118325078-A Preparation method and application of benzoquinone conjugated polymer 中国科学院宁波材料技术与工程研究所 2024-07-12 CN disclosed