Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965559 | 0.92 | CHRM4 (0.51) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965830 | 0.89 | CHRM4 (0.49) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965749 | 0.87 | CHRM4 (0.50) | CHRM4DRD2HTR1AHTR2APOLB | |
| SCHEMBL30965750 | 0.84 | POLB (0.42) | CHRM4POLBACHECA1CA2 | |
| SCHEMBL30965693 | 0.83 | HTR1A (0.44) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965686 | 0.83 | CHRM4 (0.53) | CHRM4DRD2HTR1AHTR2AGAA | |
| SCHEMBL30965733 | 0.82 | CHRM4 (0.54) | CHRM4DRD2HTR1AHTR2AGAA | |
| SCHEMBL30965580 | 0.82 | CHRM4 (0.43) | CHRM4DRD2HTR1AHTR2AACHE | |
| SCHEMBL30965765 | 0.78 | MAPT (0.44) | CHRM4DRD2HTR1AHTR2APOLB | |
| SCHEMBL30965560 | 0.77 | CHRM4 (0.59) | CHRM4DRD2HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |