Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135712 | 0.93 | MAPT (0.45) | MAPTCHRM4POLBALDH1A1LMNA | |
| SCHEMBL30965749 | 0.91 | CHRM4 (0.50) | MAPTDRD2HTR1AHTR2ACHRM4 | |
| SCHEMBL30965693 | 0.90 | HTR1A (0.44) | DRD2HTR1AHTR2ACHRM4ALDH1A1 | |
| SCHEMBL30965798 | 0.87 | DRD2 (0.43) | MAPTDRD2HTR1AHTR2APOLB | |
| SCHEMBL30965674 | 0.87 | DRD2 (0.55) | MAPTDRD2HTR1AHTR2APOLB | |
| SCHEMBL30965812 | 0.85 | CHRM4 (0.39) | MAPTDRD2HTR1AHTR2ACHRM4 | |
| SCHEMBL30965716 | 0.85 | HTR1A (0.45) | DRD2HTR1AHTR2ACHRM4ALDH1A1 | |
| SCHEMBL30135724 | 0.85 | ENPP2 (0.40) | MAPTDRD2HTR1AHTR2ACHRM4 | |
| SCHEMBL30965750 | 0.83 | POLB (0.42) | MAPTCHRM4POLBALDH1A1ACHE | |
| SCHEMBL30135895 | 0.82 | CTSL (0.41) | MAPTCHRM4ALDH1A1LMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |