Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965545 | 0.92 | DPP4 (0.40) | KCNH2DPP4DPP7ENPP2ATXN2 | |
| SCHEMBL30965750 | 0.89 | POLB (0.42) | ACHECA1CA2FFAR4SMPD3 | |
| SCHEMBL30135895 | 0.87 | CTSL (0.41) | KCNH2DPP4DPP7ENPP2ATXN2 | |
| SCHEMBL30965617 | 0.84 | CA1 (0.38) | ACHECA1CA2FFAR4SMPD3 | |
| SCHEMBL30135811 | 0.84 | DPP4 (0.42) | FFAR4KCNH2DPP4DPP7ENPP2 | |
| SCHEMBL30965716 | 0.84 | HTR1A (0.45) | KCNH2DPP4DPP7ENPP2ATXN2 | |
| SCHEMBL30965642 | 0.84 | CHRM4 (0.44) | KCNH2DPP4DPP7ENPP2ATXN2 | |
| SCHEMBL30965830 | 0.83 | CHRM4 (0.49) | ACHECA1CA2SMPD3KCNH2 | |
| SCHEMBL30965812 | 0.83 | CHRM4 (0.39) | ACHEKCNH2DPP4DPP7ENPP2 | |
| SCHEMBL30135712 | 0.82 | MAPT (0.45) | FFAR4KCNH2DPP4DPP7ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |