Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.43 |
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965545 | 0.92 | DPP4 (0.40) | HTR1ADRD2HTR2ACHRM4DPP4 | |
| SCHEMBL30965686 | 0.90 | CHRM4 (0.53) | HTR1ADRD2HTR2ACHRM4DPP4 | |
| SCHEMBL30965693 | 0.89 | HTR1A (0.44) | HTR1ADRD2HTR2ACHRM4DPP4 | |
| SCHEMBL30965765 | 0.85 | MAPT (0.44) | HTR1ADRD2HTR2ACHRM4ENPP2 | |
| SCHEMBL30965796 | 0.84 | ACHE (0.41) | DRD2HTR2ACHRM4DPP4DPP7 | |
| SCHEMBL30135895 | 0.83 | CTSL (0.41) | CHRM4DPP4DPP7KCNH2ENPP2 | |
| SCHEMBL30965830 | 0.82 | CHRM4 (0.49) | HTR1ADRD2HTR2ACHRM4KCNH2 | |
| SCHEMBL30965812 | 0.81 | CHRM4 (0.39) | HTR1ADRD2HTR2ACHRM4DPP4 | |
| SCHEMBL30965733 | 0.81 | CHRM4 (0.54) | HTR1ADRD2HTR2ACHRM4DPP4 | |
| SCHEMBL30965642 | 0.81 | CHRM4 (0.44) | CHRM4DPP4DPP7KCNH2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658658-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | Uppthera, Inc. (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024162828-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2024-08-08 | — | — | WO | disclosed |