Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305562 | 0.94 | GAA (0.65) | GAASMN1; SMN2POLBLMNANPC1 | |
| SCHEMBL23471096 | 0.92 | POLB (0.58) | SMN1; SMN2POLBLMNAEPHX2HDAC2 | |
| Hydrochloric Acid SCHEMBL6421806 | 0.92 | GAA (0.63) | GAASMN1; SMN2POLBLMNANPC1 | |
| SCHEMBL1246967 | 0.87 | LMNA (0.61) | GAASMN1; SMN2POLBLMNANPC1 | |
| Thiosulfuric Acid SCHEMBL11092443 | 0.84 | HDAC3 (0.58) | GAASMN1; SMN2POLBLMNANPC1 | |
| Thiosulfuric Acid SCHEMBL11092446 | 0.84 | HDAC3 (0.54) | GAASMN1; SMN2POLBLMNANPC1 | |
| SCHEMBL620074 | 0.83 | POLB (0.66) | POLBLMNAKMT2AHDAC4HDAC6 | |
| SCHEMBL3192014 | 0.83 | LMNA (0.77) | GAASMN1; SMN2POLBLMNANPC1 | |
| SCHEMBL6716169 | 0.83 | NPC1 (0.66) | SMN1; SMN2POLBLMNANPC1RAB9A | |
| SCHEMBL11251484 | 0.83 | LMNA (0.61) | GAASMN1; SMN2POLBLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895637-B2 | Environment-friendly antifoulants for the prevention of biofouling | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2014-11-25 | — | — | US | claimed |
| US-20140051751-A1 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-20 | — | — | US | claimed |
| US-8575230-B2 | Environment-friendly antifoulants for the prevention of biofouling | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2013-11-05 | — | — | US | claimed |
| US-20100256256-A1 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-10-07 | — | — | US | claimed |
| WO-2008130558-A2 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2008-10-30 | — | — | WO | claimed |
| US-8895637-B2 | Environment-friendly antifoulants for the prevention of biofouling | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2014-11-25 | — | — | US | disclosed |
| US-20140051751-A1 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-20 | — | — | US | disclosed |
| US-8575230-B2 | Environment-friendly antifoulants for the prevention of biofouling | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2013-11-05 | — | — | US | disclosed |
| US-20100256256-A1 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-10-07 | — | — | US | disclosed |
| WO-2008130558-A2 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051751-A1 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | TRPV1, CNR2, CNR1 | GAA 3879/4885SMN1; SMN2 3829/4885POLB 4672/4885 |
| US-20100256256-A1 | ENVIRONMENT-FRIENDLY ANTIFOULANTS FOR THE PREVENTION OF BIOFOULING | TRPV1, CNR2, CNR1 | GAA 3879/4885SMN1; SMN2 3829/4885POLB 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.