SCHEMBL31031049

SCHEMBL31031049

NCC(=O)NC(=O)[C@@]1(n2cnc3c(NC(=O)CN)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 2/20 0.39
▸ ADORA2A P29274 2/20 0.38
▸ ADORA3 P0DMS8 2/20 0.38
▸ ADORA1 P30542 2/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ ADORA2B P29275 1/20 0.38
▸ LMNA P02545 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17627818 0.91 RXFP1 (0.39) SLC29A1ADORA2AADORA3ADORA1RXFP1
SCHEMBL30705001 0.91 RXFP1 (0.39) SLC29A1ADORA2AADORA3ADORA1RXFP1
SCHEMBL15798672 0.89 ADORA3 (0.45) SLC29A1ADORA2AADORA3ADORA1ADORA2B
SCHEMBL30968983 0.82 RXFP1 (0.39) SLC29A1ADORA2AADORA3ADORA1RXFP1
SCHEMBL29137662 0.80 SLC29A1 (0.42) SLC29A1ADORA2AADORA3ADORA1ADORA2B
SCHEMBL28475028 0.80 SLC29A1 (0.46) SLC29A1ADORA2AADORA3ADORA1RXFP1
SCHEMBL31675871 0.78 AHCY (0.41) ADORA2AADORA3ADORA1ADORA2B
SCHEMBL28824008 0.78 ADORA2A (0.43) SLC29A1ADORA2AADORA3ADORA1ADORA2B
SCHEMBL16987222 0.76 TARS1 (0.38) SLC29A1ADORA1RXFP1LMNATSHR
SCHEMBL28564130 0.76 TARS1 (0.38) SLC29A1ADORA1RXFP1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119497627-A Replicon compositions and methods of using the same for treating diseases 生物技术公司 2025-02-21 — — CN disclosed
CN-118451194-A Methods for determining mutations for enhancing the function of modified replicable RNAs and related compositions and uses thereof 生物技术公司 2024-08-06 — — CN disclosed
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