Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969262 | 0.84 | HRH3 (0.65) | HRH3KDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL6978473 | 0.79 | HRH2 (0.59) | HRH3KDM4EHRH2HRH1 | |
| SCHEMBL14287757 | 0.79 | PSMB1 (0.57) | HRH3KDM4EALDH1A1PSMB1PSMB5 | |
| SCHEMBL3026592 | 0.78 | PSMB1 (0.75) | HRH3KDM4EPSMB1PSMB5PSMB2 | |
| SCHEMBL6985511 | 0.78 | HRH3 (0.65) | HRH3HRH2HRH1 | |
| SCHEMBL30969254 | 0.78 | HRH3 (0.88) | HRH3KDM4EALDH1A1LMNAHRH2 | |
| SCHEMBL1978047 | 0.77 | HRH3 (0.78) | HRH3KDM4EHRH2HRH1PSMB1 | |
| SCHEMBL22048752 | 0.77 | HRH3 (0.62) | HRH3KDM4EHRH2HRH1PSMB1 | |
| SCHEMBL6983437 | 0.77 | HRH3 (0.64) | HRH3HRH2HRH1 | |
| SCHEMBL6986499 | 0.77 | HRH4 (0.67) | HRH3KDM4EALDH1A1HRH1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642766-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | disclosed |