Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.77 |
| ▸ | CTSL | P07711 | 2/20 | 0.76 |
| ▸ | CTSS | P25774 | 1/20 | 0.76 |
| ▸ | CTSK | P43235 | 1/20 | 0.76 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.70 |
| ▸ | TACR1 | P25103 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.62 |
| ▸ | ITGAL | P20701 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003555 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL29367687 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL850438 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30976323 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| Hydrochloric Acid SCHEMBL31472643 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30699849 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| Fluoride SCHEMBL7445962 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| Fluoride SCHEMBL7445954 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL11403615 | 0.96 | ACE (0.84) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL27871524 | 0.96 | CTSL (0.76) | ACECTSLCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063354-A | Reduction-response chemotherapy-immunotherapy prodrug, nano micelle and preparation method | 烟台药物研究所 | 2023-05-05 | — | — | CN | claimed |
| EP-0449884-A4 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | — | 1991-10-30 | — | — | EP | claimed |
| EP-0449884-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990006937-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | claimed |
| US-20240197666-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | US | disclosed |
| US-11912687-B2 | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof | Board of Trustees of the Southern Illinois University (US) | 2024-02-27 | — | — | US | disclosed |
| EP-4313095-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-Gen Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117098544-A | Diterpenoid compounds acting on Protein Kinase C (PKC) | K-GEN治疗股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20230322689-A1 | IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | SunVax mRNA Therapeutics Inc. (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230322689-A1 | IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | SunVax mRNA Therapeutics Inc. (US) | 2023-10-12 | — | — | US | disclosed |
| CN-116768855-A | Aromatic amino acid compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |
| EP-3634406-B1 | 3,4,5-TRISUBSTITUTED-1,2,4-TRIAZOLES AND 3,4,5-TRISUBSTITUTED-3-THIO-1,2,4-TRIAZOLES AND USES THEREOF | BOARD OF TRUSTEES OF THE SOUTHERN ILLINOIS UNIV ON BEHALF OF SOUTHERN ILLINOIS UNIV EDWARDSVILLE (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-0336356-A2 | Derivatives of tryptophan as CCK antagonists | ABBOTT LABORATORIES (US) | 1989-10-11 | — | — | EP | disclosed |
| EP-0190588-A1 | Quinazolino-1,4-benzodiazepin-6,9-diones, processes for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-08-13 | — | — | EP | disclosed |
| US-4554272-A | CHOLECYSTOKININ INHIBITORS | MERCK & CO., INC. (US) | 1985-11-19 | — | — | US | disclosed |
| EP-0011366-A2 | Synthetic peptides, their preparation, pharmaceutical formulations containing them and intermediates for their preparation | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4202802-A | PREFERENTIAL INHIBITION OF SCRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4199501-A | INHIBITORS OF SECRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4199500-A | INHIBITORS OF SECRETION OF GROWTH HORMONE | ELI LILLY AND COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-3971736-A | HEXA- AND HEPTA-PEPTIDES, ANTIINFLAMMATORY, ANTIULCER, ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322689-A1 | IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | PHOSPHO1, SGMS1, PLIN3 | ACE 4017/4885CTSL 4397/4885CTSS 3636/4885 |
| US-11912687-B2 | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof | SSTR4, SSTR5, SSTR3 | ACE 3710/4885CTSL 3372/4885CTSS 2640/4885 |
| US-20240197666-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | PRKCA, PRKCB, PRKCI | ACE 4672/4885CTSL 2236/4885CTSS 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.