Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.75 |
| ▸ | CTSL | P07711 | 2/20 | 0.74 |
| ▸ | CTSS | P25774 | 1/20 | 0.74 |
| ▸ | CTSK | P43235 | 1/20 | 0.74 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.69 |
| ▸ | TACR1 | P25103 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | ECE1 | P42892 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL7445962 | 1.00 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL850438 | 0.99 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL1486167 | 0.99 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL29367687 | 0.99 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL1003555 | 0.99 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30976323 | 0.99 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30699849 | 0.98 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| Hydrochloric Acid SCHEMBL31472643 | 0.98 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL11403615 | 0.95 | ACE (0.84) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL27902245 | 0.95 | CTSL (0.76) | ACECTSLCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703106-A | TREATING VARIOUS CARDIOVASCULAR, UROGENITAL, BRAIN DISORDERS | JAPAT LTD. (CH) | 1997-12-30 | — | — | US | disclosed |
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | disclosed |